This work is now published at JVI (journals.asm.org/doi/10.1128/...), with some new data (effect is mediated by HA, and is not a consequence of bulk down regulation of cell surface sialic acid levels) and an additional first author (Sara Jaffrani!)
Influenza A is a major human pathogen, which poses risks through both the continuous
circulation of “seasonal” influenza viruses (H1N1 and H3N2 subtypes) as well as the
emergence of novel pandemic str...
I'm very excited to share the latest work from my group, led by @ahturner934.bsky.social. We revisited one of my favorite proteins (Rab11) and its role in influenza infection& discovered surprising new things. Rab11B is required for entry of current H3N2 isolates! 1/n www.biorxiv.org/content/10.1...
www.biorxiv.org
As an obligate intracellular parasite, influenza A virus (IAV) depends on host proteins to complete several important functions, including trafficking viral proteins throughout the cell. Previous work...
