Scientist, synthetic immunologist, loves minimalism. Interested in innate immunity, inflammasomes, cell death, inflammation, autoinflammatory diseases and cancer.
Iva Hafner Bratkovič
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This gift is related to the work spearheaded by Taja Železnik Ramuta and @rjerala.bsky.social @kemijski.bsky.social
www.biorxiv.org/content/10.1...
Never expected to be mentioned in the Nature Briefing www.nature.com/immersive/d4...
Huge congratulations to @elvirab.bsky.social on an outstanding PhD viva! A well-deserved achievement reflecting years of hard work, perseverance, scientific curiosity, and intellectual growth. It has been a privilege to mentor this journey. Excited to see what comes next. 🎓👏
One month left until early registration closes! Apply now if you would like to be considered for a talk.
It will be an amazing conference bringing together leading scientists in the field of protein design.
[Protein Emoji]
We are excited to have our new paper out: Tethering of the pathogen sensor caspase-4 to the endomembrane damage sensor galectin-8 poises the host to rapidly detect pathogens that breach the endolysosomal network.
www.cell.com/cell-reports... #innate_immunity #inflammasome #celldeath #immunoSky 1/2
Belated post of my macaron centrepiece from last week’s @ciiid-hudson.bsky.social Christmas party – “the cells of CiiiD”. A lot of work to produce this undetermined number of macarons (I lost count) 🙃 Big thanks to @biorender.bsky.social who I used to make the templates! @hudsonresearch.bsky.social
Congrats @lauracanaday.bsky.social @andypedsid.bsky.social @hafeldman17.bsky.social
& team on our newest publication @jimmunol.bsky.social
Refined cell transfer model reveals roles for Ascl2 and Cxcr3 in splenic localization of mouse NK cells during virus infection
academic.oup.com/jimmunol/adv...
NLRP3 inflammasomes can assemble on most organelles. A beautiful study by Hafner et al demonstrate the flexibility of organelles that can support inflammasome activation. Kudos to the authors on an intriguing study.
www.nature.com/articles/s41...
@ivahb.bsky.social @elvirab.bsky.social
A glycan-based adjuvant expands the breadth and duration of protection of mRNA-based vaccines
www.nature.com/articles/s41... @lozanzi.bsky.social @harvardmed.bsky.social
@natimmunol.nature.com
Subcellular location of NLRP3 is not essential, but clustering on different scaffolds is. This explains how NLRP3 can react to so many diverse stress signals.
9/9
Nature asked about your most memorable scientific gifts. You delivered.
www.nature.com
Early bird registration for 𝐄𝐔 𝐑𝐨𝐬𝐞𝐭𝐭𝐚 𝐂𝐨𝐧 𝟐𝟎𝟐𝟓 is open! 🎉🎉🎉
Come join us for three days of protein design fun! (October 20-22, 2025)
Direct registration link: pretix.eu/SBD/RCon2025/
Website: europeanrosettacon.org
We are looking forward to seeing you!
Please share this far and wide:)
Strategies for detecting and controlling protein interactions play a critical role in gaining insight into molecular mechanisms of biological processes and for the control of cellular processes. Condi...
NLRP3 inflammasome activation is critical for the induction of protective immunity, but molecular insights are still lacking. Here, the authors express NLRP3 variants targeted to different cellular lo...
Shivcharan et al. report that endosomal damage sensing by the danger receptor galectin-8
licenses noncanonical inflammasome activation and pyroptosis during intracellular
bacterial infections in human...
www.cell.com
Excited to share preprint (currently in revision) from the PhD dissertation of my former student @lauracanaday.bsky.social. Thanks to
@andypedsid.bsky.social @hafeldman17.bsky.social
and the rest of the team for their hard work.
biorxiv.org/content/10.1...
