📣 Paper alert:
Ras signalling at the actin cortex: Coordinating local and global changes to cell morphology.
@helenkmatthews.bsky.social
pubmed.ncbi.nlm.nih.gov/41275567/
Ras proteins modulate key cellular signalling pathways and drive excessive proliferation when mutated in cancer. However, they also influence actin cytoskeleton organisation. In the model organism Dictyostelium, domains of active Ras pattern the plasma membrane and locally reorganise the actin corte …