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Group leader @TU München. Interested in cell biology, cell polarity, fertilization and plants in general. Big fan of microscopy!
Philipp Denninger









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Looking for an efficient way to clone and purify your proteins? Check out our new Vector-Set with lots of different tags, especially useful for GreenGate users. Including a low-cost DIY HRV3C-protease (PreScission) purification strategy. doi.org/10.64898/202...
New Preprint: Plasma membrane nanoscale dynamics of Arabidopsis leucine-rich repeat receptor kinase complexes (2026) https://www.tsl.ac.uk/publications/164874
Hope to see all of you (again) at our international #BT2026 organized by #MBP2026 @molplantsci.bsky.social co-host Christopher Grefen 📍 @ruhr-uni-bochum.de in Bochum, Germany. 📆 6 – 10 September 2026 bsky.app/profile/plan...
Abstract submission deadline extended for 2 types of posters to present your #plantsci work at our #BT2026 to an international plant science audience 📍 in Bochum, Germany 📅 6-10 Sept 2026 www.deutsche-botanische-gesellschaft.de/u/BT2026ext
What a treat to see the work from Camila Goldy @camilagoldy.bsky.social et al., @rdplab.bsky.social @ensdelyon.bsky.social now published 🫶 www.science.org/doi/10.1126/...
New Brief Communication: "A CRISPR-based sequence proximity binding protein labelling system for scanning upstream regulatory proteins" rdcu.be/eZLUP CRISPR-based proximity labelling system to profile DNA-binding proteins such as PIF4 transcription factor .
#PlantSciConfi Registration open for International Conference of our German Society for Plant Sciences Botanik-Tagung #BT2026 in #Bochum, Germany 6 – 10 September 2026 www.deutsche-botanische-gesellschaft.de/u/82bsBT2026
Autoinhibitory calcium ATPases regulate the calcium gradient required for rapid polarized growth, say Samantha Ryken, Magdalena Bezanilla and colleagues (Dartmouth College): rupress.org/jcb/article/... #PlantBiology #Trafficking #Cytoskeleton
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A team led by @kit.edu and with significant participation from @leibnizipk.bsky.social has succeeded for the first time in specifically altering the chromosome number of Arabidopsis using CRISPR Cas - without adversely affecting plant growth. www.science.org/doi/10.1126/...
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Registration for the 13th PhD School on Plant Development is open! 🌾 🔬 🌺 🧬 🌵 🧪 Deadline: June 30, 2026 Link to registration form forms.gle/tbmUxaw2vmEn... Cost: €350.- (incl. board, lodging and social event) For details re payment and abstracts see form or homepage raissiglab.org/plantdevosch...
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Plasma membrane-localized receptors operate as dynamic signaling complexes and integrative networks, yet the spatial and temporal regulation of these interactions remain largely unknown. Here, by analyzing the components of a minimal Arabidopsis leucine-rich repeat receptor kinase network, we describe the differential diffusion and organization of receptor complex components and unveil the nanoscale spatial and temporal logic underlying the formation of receptor kinase complexes. The ligand-binding receptors FLS2 and BRI1, and the accessory receptor BIR3, are organized in plasma membrane nanodomains, within which the co-receptor BAK1 diffuses and is spatially arrested upon ligand perception. BAK1 spatial arrest relies on extracellular domain (ECD)-ECD interactions but does not require receptor complex activation. Mathematical modelling, single molecule imaging and bio-assays infer that accessory receptors maintain a dynamic pool of co-receptors in the vicinity of ligand-binding receptors to promote ligand-induced complex formation and signaling. We propose that ligand-induced receptor kinase complex formation is a deterministic process defined by the relative nanoscale spatial positioning of individual signaling and regulatory components.
doi.org
bioRxiv: Plasma membrane nanoscale dynamics of Arabidopsis leucine-rich repeat receptor kinase complexes (2026)
Actin guides plant cell division, shaping tissues in ways that defy geometric constraints.
www.science.org
The actin cytoskeleton is required to maintain plant cell division orientation against cellular geometry
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Philipp Denninger
The Sainsbury Laboratory
German Society for Plant Sciences (DBG)
German Society for Plant Sciences (DBG)
Marie-Cécile Caillaud
German Society for Plant Sciences (DBG)
The genome of Arabidopsis thaliana consists of 10 chromosomes. By inducing CRISPR-Cas–mediated breaks at subcentromeric and subtelomeric sequences, we fused entire chromosome arms, obtaining two eight...
www.science.org
CRISPR-Cas–mediated heritable chromosome fusions in Arabidopsis
Nature Plants
Journal of Cell Biology
#PlantSciConfi Registration open for International Conference of our German Society for Plant Sciences Botanik-Tagung #BT2026 in #Bochum, Germany 6 – 10 September 2026 www.deutsche-botanische-gesellschaft.de/u/82bsBT2026
Leibniz IPK
3mo
German Society for Plant Sciences (DBG)
Michael Raissig