Inlay

Profile

Group Leader @ BIH Berlin and MPI Molecular Genetics. I play around with DNA because I‘d like to know how the genome functions.

Daniel Ibrahim

An historical figure of the transcription field has gone. Founder of @igbmc.bsky.social where I started my career. A great enabler as well.

1mo

⭕️ The STRAIGHT-IN dual plasmids are now available on Addgene! 🧬 @addgene.bsky.social A full STRAIGHT-IN kit with 20+ plasmids, including everything needed to set up and run the platform, is coming soon 🔥 Stay tuned 🚀

1mo

Pierre Chambon was a great scientist. And a good man too. He alone opposed to leading British embryologists during the evaluation of a case of scientific misconduct more than 40 years ago, to defend young scientists against an establishment to which he belonged. An unforgettable lesson. RIP Pierre 💐

In 2015, the Los Angeles SPCA gave their annual National Hero Dog award to a tabby cat named Tara. Yes, you read that right, a cat was given a dog award.

1mo

And more plasmids for using STRAIGHT-IN Dual from the Galloway Lab here: www.addgene.org/browse/artic...

1mo

Arnaud Krebs

Albert Blanch-Asensio

We are over the moon! 🎈 Dr. Marieke Oudelaar joins the MPI-IE as a new #MaxPlanck Director, heading the newly established Department of Genome Biology She studies how the 3D folding of DNA controls gene expression – more details below ⬇️ Welcome to #Freiburg, @mariekeoudelaar.bsky.social!

Excellent opportunity @mrc-lms.bsky.social for a human physiologist to start their own group. Deadline 4th May. Core funding, excellent package. Please repost! lms.mrc.ac.uk/work/vacanci...

MyPet Health by Vetcation

15d

Join is in Budapest in October! For the 6th time, all things epigenetics, gene and genome regulation and more. A fantastic opportunity to present, to talk to speakers and colleagues in a friendly, informal setting at a great location. Please note, travel grant deadline will expire soon.

1mo

Denis Duboule

10d

Addgene

www.ie-freiburg.mpg.de

lms.mrc.ac.uk

Marieke Oudelaar becomes new Director at MPI-IE in Freiburg

Programme Leader Track - MRC Laboratory of Medical Sciences

22/n On a personal note, I’ll soon start an independent research group in the Genome Biology Unit at EMBL Heidelberg. If you enjoy this type of work and want to engineer genomes at the largest scale, please reach out! jonas-koeppel.github.io/koeppellab/ www.embl.org/groups/koepp...

1/n What fraction of the human genome is essential for cells? Excited to share our preprint that explores this question by combining an unusual CRISPR system, phage promoters, and thousands of deletion launchpads. @sudpinglay.bsky.social @jshendure.bsky.social www.biorxiv.org/content/10.6...

Max Planck Institute of Immunobiology and Epigenetics

Ferenc Mueller

Genome engineering research led by Jonas Koeppel, developing scalable technologies to design structural variants and study mammalian genome function.

jonas-koeppel.github.io

Koeppel Lab | Structural Variation and Genome Engineering

www.addgene.org

Alexis Barr

Addgene: Gene syntax defines supercoiling-mediated transcriptional feedback.

Video

Jonas Koeppel

Need a solution for multi-transgene integration? Check out the STRAIGHT-IN Dual platform! Thanks to the Galloway and Davis Labs for sharing the plasmids: www.addgene.org/browse/artic...

1mo

#RIP Pierre Chambon (1931-2026) 1963 PARP 1970 RNA Pol II 1975 Nucleosome 1977 Split genes 1980 Promoter 1983 enhancer 1986 Nuclear receptor

1mo

Addgene

www.addgene.org

Addgene: STRAIGHT-IN Dual: a platform for dual single-copy integrations of DNA payloads and gene circuits into human induced pluripotent stem cells.

Alexis Verger 🧬🧫🧪

Post 1/3 🧵 Our latest work is out at @natbiomedeng.nature.com!🚀 We present STRAIGHT-IN Dual — a platform for precise, allele-specific integration of two large DNA payloads into human iPSCs, enabling more sophisticated control of complex genetic programs. Link📝: www.nature.com/articles/s41... 👇

1mo

Albert Blanch-Asensio