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This week, we installed a first-of-its-kind quantum sensing platform in our lab! As part of our lab’s mission to advance #interdisciplinary research, we’re bringing #quantum sensing into #pharmacology. #ChemSky

Enhanced autoionization of #water at phospholipid interfaces. dx.doi.org/10.1021/jp31... #Hydration strongly affects the molecular and electronic structure of membrane #phospholipids. doi.org/10.1063/1.36... Vibrational lifetimes of hydrated phospholipids. doi.org/10.1209/0295...

My laboratory has an open postdoctoral position in the field of biomolecular condensate mechanochemistry! Please inquire if you are interested in interdisciplinary, cutting-edge research! www.mashaghilab.org/vacancies (Deadline: February 8, 2026) #ChemSky #Mechanobiology #Biomolecular_Condensate

Interest grows in #quantum physics for #biology. Sharing our early quantum calculations on #biomolecular structure, dynamics, and electrical properties: Interfacial water facilitates energy transfer by inducing extended vibrations in membrane lipids. pubs.acs.org/doi/10.1021/... #ChemSky

A new study by Runfeng Lin & Sebastian Ahnerton from Cambridge University on the application of Circuit Topology in Protein Science: "Millisecond Prediction of Protein Contact Maps from Amino Acid Sequences" www.biorxiv.org/content/10.6... #ChemSky #Topology #StructuralBiology #Bioinformatics

Through a series of papers, we demonstrated the applicability of scanning probe microscopy to biomolecular condensate analysis! Droplet fusion: doi.org/10.1038/s414... Droplet rheology: doi.org/10.1016/j.xc... doi.org/10.1016/j.xp... Droplet-cell interaction: doi.org/10.1016/j.ce... #ChemSky #AFM

Delighted to share our new study, "Topological Investigation of Protein Folding and Intrinsic Disorder". We ask whether topology provides a unifying structural language across the order–disorder continuum! doi.org/10.64898/202... #ChemSky #Protein #IDP #Topology #Biophysics

Press release: Light switch for life – controlling biomolecular condensate droplets with UV! Read our new article in Nature Communications! www.universiteitleiden.nl/en/news/2026... #ChemSky #BiomolecularCondensate #SoftMatter #Protocell #Polyelectrolyte

Community science: Since 1996, Alireza Mashaghi has actively advocated for collaborations between disciplines to explore new ways of addressing scientific and societal challenges. The team has a long...

The structure and autoionization of water at the water–phospholipid interface are investigated by ab initio molecular dynamics and ab initio Monte Carlo simulations using local density approximation (LDA) and generalized gradient approximation (GGA) for the exchange–correlation energy functional. Depending on the lipid headgroup, strongly enhanced ionization is observed, leading to the dissociation of several water molecules into H+ and OH– per lipid. The results can shed light on the phenomena of the high proton conductivity along membranes that has been reported experimentally.

We report the complete assignment of the vibrational spectrum of dipalmitoylphosphatidylcholine (DPPC), which belongs to the most ubiquitous membrane phospholipid family, phosphatidylcholine. We find ...

Leiden researchers have discovered a surprising new way to shape and control tiny droplets of molecules found in living organisms. The breakthrough could lead to smarter biomaterials, improve drug del...