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New PRECISION consortium research maps early DNA changes in DCIS, pointing to SHOREs and ecDNA as possible signs of more aggressive evolution. Read in Nature Communications: www.nature.com/articles/s41...
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Predicting progression from ductal carcinoma in situ (DCIS) to invasive breast cancer remains challenging. Here, deep whole genome sequencing of DCIS samples highlights possibilities for personalized ...
www.nature.com
High-depth whole genome sequencing of premalignant breast lesions reveals rearrangement hotspots and personalized management opportunities - Nature Communications
Netherlands Cancer Institute