Structures of telomerase with allosteric inhibitor BIBR1532 reveal an unexpected mode of inhibition and unique insights into telomerase mechanism
www.nature.com/articles/s41...
Telomerase, the ribonucleoprotein that maintains telomere ends, is upregulated in most cancer cells, making it a promising oncology target. Cryo-electron microscopy structures of telomerase with allos...
