Glucose deprivation promotes OXCT1 phosphorylation and nuclear translocation, which leads to repressed transcription of MHC-I and chemokine genes and reduced immunotherapy responsiveness
www.nature.com/articles/s41...
Metabolic reprogramming in cancer cells can contribute to responsiveness to immunotherapy. In this study, glucose deprivation in hepatocellular carcinoma cells was found to promote OXCT1 S113 phosphor...
