Oxygen-dependent and photoreactive APEX2-based proximity labeling using a chemically evolved biotin probe for applications in living cells and in vivo
www.nature.com/articles/s41...
The H2O2 dependence of APEX2 and the toxicity of H2O2 hinder the use of APEX2-based proximity labeling in vivo. Now, APEX2 is rendered blue light activated with oxygen-dependent and low-H2O2-responsiv...
