Nature research paper: Structure of the pre-initiation complex explains CMGE biogenesis
go.nature.com/4ab2Fkl
Cryo-electron microscopy and biochemical reconstitution experiments in yeast provide insight into the assembly of the CMGE complex, a helicase that establishes bidirectional DNA replication in eukaryotic cells, and elucidate the role of the firing factor Sld2.