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"Here, we confirm profound diet-PI3K anticancer synergy but show that it is, surprisingly, unrelated to diet macronutrient composition. Instead, the diet-PI3K interaction involves microbiome metabolism of ingested phytochemicals."
Diet can impact anticancer drug activity. A classic example in rodents is a ketogenic
diet enhancing PI3K inhibitor activity. Here, we show that phytochemicals and their
microbiome derivatives, rather...
