Professor of Cancer Virology, University of Leeds.
Co-Chair, Independent SAGE
Steve Griffin
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I and @independentsage.bsky.social advocated kids vax vs SARS2 since day 1.
Even when transiently available to u12s, they were sold as a damp squib by those in authority.
As vax coverage dwindles, the lack of foresight gets harder to reconcile.
#LongCovidKids is a major neglected issue 💔
That dynamic does not apply to most other variants. It could help explain why BA.3.2 has been around for so long and may suggest it has long-term staying power, especially if, beyond its antibody-evasion advantage, it is particularly well adapted to infecting young children.
#BA32
This means its primary host population is effectively renewed every four years, with new cohorts of largely immunologically naive children entering the population, aside from maternal antibodies.
BA.3.2 - a "forever" variant?
I've always wondered why BA.3.2 has persisted for such a long time.
Now we know that it mainly targets the 0-4-year age group, and we know why. Could that explain its persistence?
Taking the idea one step further:
Could the establishment of a reservoir in young children- as discussed in my previous post - be one of the routes by which SARS-CoV-2 transitions into endemic circulation?
Finally.
BBC News - Meningitis B vaccine to be offered to a million young people
www.bbc.co.uk/news/article...
