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David Bartel's lab @WhiteheadInst @MIT @HHMI | microRNAs, mRNAs, and other RNAs
David Bartel's Lab








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Our work investigating mRNA 3' UTRs that trigger target-directed miRNA degradation is now published! genesdev.cshlp.org/content/earl...
2mo
A biweekly scientific journal publishing high-quality research in molecular biology and genetics, cancer biology, biochemistry, and related fields
mRNA 3′ UTRs direct microRNA degradation to participate in imprinted gene networks and regulate growth
genesdev.cshlp.org
David Bartel's Lab
In budding yeast cultured under saturation or other prolonged stresses, ~10% of introns accumulate post-splicing as stable, linear RNAs that are protected by the spliceosome. We set out to understand how these stable introns remain associated with the spliceosome and escape canonical RNA decay.(2/4)
Huge thanks to @maxewilkinson.bsky.social for making this work possible! (4/4)