Studying the stream of consciousness during sleep and wakefulness
Neuroscientist at the Paris Brain Institute
Chargé de Recherche Inserm
Adjunct Senior Research Fellow at Monash University
Co-Editor-in-Chief of Neuroscience of Consciousness (OUP)
Thomas Andrillon
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"I no longer steer; I commission."
🥳 New article by @champetier-pierre.bsky.social
In subjective cognitive decline, resting-state #sleep like slow waves predict:
1) amyloid and neurodegeneration status 🧠
2) memory performance 📝
3) conversion to amyloid positivity within 2 years
alz-journals.onlinelibrary.wiley.com/doi/10.1002/...
No they don't! Humans report being conscious half of the time when awoken from NREM sleep.
The NREM/REM, conscious/unconscious dichotomy has been thoroughly debunked.
It's time we stop oversimplifying the relationship between sleep and consciousness!
Thomas Andrillon
Thomas Andrillon
Our scientifically accessible book chapter "Spontaneous Thoughts and Experiences across Wakefulness and Sleep" is now available. Wonderfully led by @parboulakis.bsky.social, w/ @jdsitt.bsky.social and @thomasandrillon.bsky.social. Edited by #LuciaMelloni and #UmbertoOlcese👇👇👇
Thomas Andrillon
What happens when the brain slips into a microsleep?
An example from a highly drowsy participant showing a brief loss of responsiveness (at time 0s). Details of the research: www.biorxiv.org/content/10.6...
Following a microsleep, arousal-promoting subcortical nuclei come back online in a beautiful sequence, restoring wakefulness and responsiveness. This video captures such a recovery in a drowsy participant performing an attention task.
Details:
www.biorxiv.org/content/10.64898/2026.05.26.728061v1
New paper from our group: using simultaneous EEG-fMRI, we investigated the neural mechanisms underlying individual NREM sleep slow waves. Our findings suggest that slow waves are not a homogeneous phenomenon and may reflect distinct physiological processes.
www.nature.com/articles/s42...
Retrouvez la conférence de Delphine Oudiette du @institutducerveau.bsky.social à la tribune de l'Académie " Au-delà de la dichotomie veille-sommeil : vers une nouvelle vision des états de conscience" #Medsky 🧪 👩🔬#neuroskyence
youtu.be/9rQXSclXS0E
🥳📰 Our new paper on sleep-like slow waves (resting-state EEG recordings) in older adults is now out in A&D journal! 🥳📰
Thanks @alzheimer-recherche.org for support and to co-authors!
@alzassociation.bsky.social
@institutducerveau.bsky.social
alz-journals.onlinelibrary.wiley.com/doi/10.1002/...
INTRODUCTION
Growing evidence supports a critical role of sleep slow waves (SW) in Alzheimer's disease (AD). However, wake SW (sleep-like SW potentially reflecting local intrusions of sleep) remain .....
Blank, and you might miss it.
Our chapter, “Spontaneous Thoughts and Experiences across Wakefulness and Sleep,” for the upcoming book The Scientific Study of Consciousness: Experimental & Theoretical Approaches, is now available at www.horizon-minds.com.
Physiology of Cognition Lab
Video
I've had access to Claude 5 Fable for a bit. A genuine jump in capability, I could feed it a 15 page design document for a project and it would work for 9+ hours and deliver terrific results.
But working with it is weird & weirder is coming
Lots of examples: open.substack.com/pub/oneusefu...
Ewa Beldzik
Ewa Beldzik
Thalamic oscillations distinguish natural states of consciousness in humans
Nature Human Behaviour, Published online: 27 May 2026; doi:10.1038/s41562-026-02446-zChowdhury et al. report the discovery of a 19–45-Hz thalamic oscillation that is present during human wakefulness and REM sleep, but not NREM sleep.
Using simultaneous EEG-fMRI, we identify two types of NREM slow waves with distinct thalamic profiles. Large, synchronized waves involve early thalamic activation and arousal markers, whereas smaller ...
INTRODUCTION Growing evidence supports a critical role of sleep slow waves (SW) in Alzheimer's disease (AD). However, wake SW (sleep-like SW potentially reflecting local intrusions of sleep) remain ...
🥳 New article by @champetier-pierre.bsky.social
In subjective cognitive decline, resting-state #sleep like slow waves predict:
1) amyloid and neurodegeneration status 🧠
2) memory performance 📝
3) conversion to amyloid positivity within 2 years
alz-journals.onlinelibrary.wiley.com/doi/10.1002/...
Blank, and you might miss it.
Our chapter, “Spontaneous Thoughts and Experiences across Wakefulness and Sleep,” for the upcoming book The Scientific Study of Consciousness: Experimental & Theoretical Approaches, is now available at www.horizon-minds.com.
INTRODUCTION
Growing evidence supports a critical role of sleep slow waves (SW) in Alzheimer's disease (AD). However, wake SW (sleep-like SW potentially reflecting local intrusions of sleep) remain .....
