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by @danabra.mov
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by @danabra.mov
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by @jimpick.com
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by @atsui.org
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Honoured to see our @natimmunol.nature.com study highlighted in a thoughtful @jhepatology.bsky.social commentary on the IL-27/Kupffer cell axis in chronic HBV — a great summary of why tissue immunity matters and of our work. Paper: tinyurl.com/yt652mxa Commentary: tinyurl.com/56pke5x5
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www.nature.com
Here the authors show that CD4+ effector T cells prevent or reverse CD8+ T cell dysfunction by licensing Kupffer cells to trigger IL-27 production, defining a liver-specific immune circuit and a poten...
CD4+ T cells license Kupffer cells to reverse CD8+ T cell dysfunction induced by hepatocellular priming - Nature Immunology
Iannacone Lab