Latest from the lab, led by @ara-donia.bsky.social and @juliavdkorput.bsky.social
Huge team effort, with immense contributions by friends from nearby and around the globe.
www.science.org/doi/10.1126/...
Led by Marcus Keatinge
"Mislocalisation of TDP-43 to the cytoplasm of either neurons or oligodendrocytes causes axonopathy and dysmyelination"
www.biorxiv.org/content/10.1...
www.nature.com/articles/s41...
I am delighted to see this work published. A big thanks to everyone, particularly the excellent supervision of @lyons-lab.bsky.social, the work of co-first author @juliavdkorput.bsky.social and wonderful collaborators in Amsterdam and Oregon.
www.science.org/doi/10.1126/...
Latest offering. How myelin ensheathes axons!
Born from chat with Dwight Bergles on "weird things" we saw oligodendrocytes do, like making "bridges" between sheaths.
Driven forward by Cody Call, Kelly Monk, and myelin folks @edinburgh-uni.bsky.social
Enjoy!
www.nature.com/articles/s41...
alert! fundamental myelin biology - led by the amazing Yevgeniya Mironova and Dwight Bergles www.science.org/doi/10.1126/...
Thrilled that our paper is now published. It’s been a real privilege to work on this project together with co-first author @ara-donia.bsky.social, under the supervision of @lyons-lab.bsky.social, and with such an outstanding team in Edinburgh and internationally!
www.science.org/doi/10.1126/...
Brilliant Kick off day #ISNASN2025
@neurochemistry.org with the best conference views ever 😎
Glad to be part of it #TogetherForScience
If you wanna know more about my work on axons & zebrafish in the @lyons-lab.bsky.social join me during the poster session tmr evening (LBA45) or just reach out 🐠
Very excited to share the news today that Professor Baljit Khakh will become the new Centre Director of the UK DRI at Cardiff University!
Read our full announcement 👉 www.ukdri.ac.uk/news-and-eve...
£70 million investment in IRR spinout Trogenix to tackle aggressive cancers.
The funding will enable the rapid advancement of its pipeline of potentially curative cancer therapies across multiple treatment-resistant cancers
regeneration-repair.ed.ac.uk/ps70-million...
@edinnovations.bsky.social
The rate of axon ensheathment varies within individual myelinating processes, resulting in chains of myelin sheaths connected by bridges consisting of thin cytoplasmic processes that provide ...
The homeostasis of myelin in the central nervous system is highly regulated, but the underlying mechanisms are unclear. Here, the authors show that the FBXW7 protein has a role in constraining myelin ...
Myelin damage is a hallmark of several neurological disorders, but how it occurs remains to be fully understood. In this study, we found that early damage in zebrafish and rodent demyelination models ...
Oligodendrocytes form myelin sheaths around axons to enable rapid signaling within neural circuits. The generation of new oligodendrocytes through differentiation of oligodendrocyte precursor cells (O...
www.science.org
Julia van de Korput
Jenn Orthmann Murphy
UK Dementia Research Institute
MariaEichelVogel.bsky.social
Institute for Regeneration and Repair
Myelin damage is a hallmark of several neurological disorders, but how it occurs remains to be fully understood. In this study, we found that early damage in zebrafish and rodent demyelination models ...
Myelin damage is a hallmark of several neurological disorders, but how it occurs remains to be fully understood. In this study, we found that early damage in zebrafish and rodent demyelination models ...
