Director of Modified Bases Research at @nanoporetech.com
EMBL-EBI alumni, keen cyclist and father of two.
Views are my own. Reposts are not endorsement.
Adrien Leger
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🚨 We’re hiring ! 🚨
Join our cutting-edge research team as a molecular biologist at @nanoporetech.com HQ in Oxford.
Perfect for a fresh PhD or MSc with a couple of years’ experience. Work at the interface of chemistry, molecular/synthetic biology and AI
👉 ejnh.fa.em2.oraclecloud.com/hcmUI/Candid...
Excited to welcome @adrienleger.bsky.social from @nanoporetech.com to our RNA Symposium! 🎤 His talk will focus on how nanopore direct RNA sequencing can reveal multiple RNA modifications at once. Secure your spot at our symposium now 👉 zurl.co/mrhKq
#RNA #ribosome #nanopore
Big improvements in modification calling accuracy - 6mA increases from Q16 to Q24
The world prefers its energy more in the form of electricity than anything else.
New HAC models are 1.4Q more accurate - a 25% error reduction
Dorado v1.0.0 introduces dramatic improvement to modified base calling speed
Our abstract submissions for London Calling 2026 are now open! If you’ve been using Oxford Nanopore technology to power the bigger and bolder research questions, we want to hear about it. Submit your abstract here: nanoporetech.com/about/events... #nanoporeconf
Adrien Leger
Our paper using Oxford #Nanopore direct RNA sequencing to identify m6A modifications on RNA isoforms in human brain is now out in Science Advances. 🧪
www.science.org/doi/10.1126/...
#NanoporeConf Lakmal Jayasinghe
ONT is the *only* sequencing technology that detects RNA modifications directly. They're now up to 8 modifications that can be detected simultaneously.
[This is something I think ONT should be shouting from the rooftops every day]
RNA barcoding is in beta testing.
Video
At London Calling, Rosemary Sinclair Dokos and Lakmal Jayasinghe shared how we’re doubling down on what matters: delivering a future-ready platform with proven performance across DNA, RNA, and now proteins. Click here to discover what’s new – and why it matters: nanoporetech.com/news/london-...
Immagina BioTechnology
Direct RNA-seq in brain reveals RNA isoform and region-specific m6A modifications, highlighting their role in gene regulation.
