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The final version of our latest paper is now published in @natcomms.nature.com! This study illustrates how #AntibioticResistance mechanisms can reshape bacterial physiology beyond resistance itself, ultimately influencing infection dynamics in clinically relevant ways🦠 www.nature.com/articles/s41...
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In this work, authors show that the loss of the carbapenem porin OprD in Pseudomonas aeruginosa reduces mucus entrapment and enhances airway epithelial barrier crossing, illustrating how antibiotic re...
www.nature.com
Carbapenem-resistance oprD mutations reshape Pseudomonas aeruginosa host-pathogen interactions during infection - Nature Communications
Pablo Laborda
New preprint out! 📣🚨 We found that loss-of-function mutations in the carbapenem entry porin OprD of Pseudomonas aeruginosa do more than confer #AntibioticResistance: they reshape the bacterial membrane and interaction with the host, enhancing epithelial colonization capacity 🦠 #Microsky
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Pablo Laborda
Carbapenem-resistance oprD mutations reshape Pseudomonas aeruginosa host-pathogen interactions during infection https://www.biorxiv.org/content/10.1101/2025.10.24.684370v1