New preprint!👇
Pyruvate secreted by P. aeruginosa acts as a signaling molecule during infection, reducing oxidative stress, dampening immune activation and promoting persistence
Bacterial metabolism isn’t just a background process but an active player in infection🦠🧫
www.biorxiv.org/content/10.6...
Chronic infections by Pseudomonas aeruginosa in people with cystic fibrosis are characterized by persistent inflammation and oxidative stress, yet the mechanisms enabling bacterial persistence are not...
