Biophysics of mitosis / mitotic spindle / chromosome segregation and aneuploidy
Head of Laboratory of Cell Biophysics at @institutrb.bsky.social, previously at @mpi-cbg.de, LENS Florence, Niels Bohr Institute, @hsph.harvard.edu, Uni Zagreb.
tolic.irb.hr
Iva Tolić
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Beyond thrilled to share that I've been elected as a member of the Croatian Academy of Sciences and Arts (HAZU)! Deeply grateful to my group at @institutrb.bsky.social, collaborators, mentors, and family, I didn't get here alone. The photo is from my associate membership, a new one coming soon! 😃
Best paper awards at the Ruđer Bošković Institute 🎉 Thrilled that four of my PhD students and I received an award for our paper “Microtubule poleward flux as a target for modifying chromosome segregation errors.”
We love SRCE (“Srce” means “Heart”), our University Computing Center and an amazing collaborator! It was great to give a talk at "Days of e-Infrastructure" and celebrate SRCE’s 55th anniversary. Happy birthday, SRCE! 🎉 #SrceDEI2026
On the way to Vienna! Looking forward to seeing longtime science friends and meeting the next generation of microscopy enthusiasts.🔬
Večernji list, 25.3.2026. Big congrats to my super talented, dedicated, and courageous young team! 👏 🩷 🔬
In the closing talk of #SpindleCroatia2026, Helder Maiato discussed how dividing cells adapt to karyotype evolution. Using Indian muntjac (2N=6/7) and Chinese muntjac (2N=46) cells, they showed that high chromosome number is a critical mitotic vulnerability.
Monica Gobran showed that when CDK1 is partially inhibited, nuclear pores begin to disassemble, but the overall structure of the nuclear envelope remains intact, similar to closed mitosis. The spindle forms outside the nucleus. #SpindleCroatia2026
Jacques Pécréaux used FRAP of the half-spindle in C. elegans and revealed that only kinetochore microtubules exhibit flux, sliding along pole-anchored ones. The flux is larger on the posterior side, reflecting the imbalance in cortical pulling forces. #SpindleCroatia2026
What an inspiring few days in Dubrovnik at #SpindleCroatia2026, which Nenad Pavin and I organized for the 4th time. Outstanding science and many warm reunions with colleagues from around the world! Huge thanks to the whole spindle community!!
