Molecular immunology lab at the University of Washington. Interests include innate immunity, host-virus interactions, RNA regulation, and genetics. All opinions are my own. Love photography
https://www.ramsavanlab.org/
https://seattle.cytokinesociety.org
Ram Savan
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Lineage-specific chromatin poising enforced by ETS-IRF composite elements determines the divergent interferon responses of plasmacytoid dendritic cells and epithelial cells https://www.biorxiv.org/content/10.64898/2026.06.05.730516v1
Lineage-specific chromatin poising enforced by ETS-IRF composite elements determines the divergent interferon responses of plasmacytoid dendritic cells and epithelial cells https://www.biorxiv.org/content/10.64898/2026.06.05.730516v1
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Our new manuscript, by lead author Gargi Mishra, shows that the IFN-I locus in pDCs is poised for rapid interferon production, as PU.1 and IRF8 establish an open chromatin architecture.
#Immunology #Interferons #InnateImmunity #Epigenetics
Hummingbird feeding the chick #birds #hummingbird #mothersday #PNW #Nisqually #photography
Join us in Copenhagen, Denmark, for #HCVFlavi2026! The international conference on Hepatitis C Virus, Flaviviruses and Related viruses.
🗓️ Dates: September 14–17, 2026
⏳Abstracts: May 12, 2026; Early Registration: June 14, 2026
hcv-flavi2026.org
#Antivirals #HCV #Flavivirus #Vaccines
Ospreys building a home to start a family. #birds #osprey #pnw #photography
