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Why do patients with CV2 autoantibodies suffer so much? Antibodies target and excite DRG neurons. @natcomms.nature.com
10mo
Geoffroy Laumet
I’m proud to share that our first paper from the lab has just been published in Nature Communications: www.nature.com/articles/s41... This work uncovers a mechanism by which autoantibodies targeting CRMP5 contribute to neuropathic pain in paraneoplastic syndromes. #PainResearch
10mo
Anti-CV2/CRMP5 autoantibodies as drivers of sensory neuron excitability and pain in rats - Nature Communications
www.nature.com
Lung and thymoma cancer patients often suffer from autoimmunity and related painful neuropathies. Here the authors show that patient-derived anti-CRMP5 autoantibody binds to rat dorsal root ganglia to...
Aubin Moutal