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In our newest paper published in @natcomms.nature.com, we show that DAF-16/FOXO and HLH-30/TFRB promote healthy aging, in part, by activating lipid metabolism genes that remodel lysosomes into tubular networks (more in comments below). www.nature.com/articles/s41...
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This study reveals that transcription factors DAF-16/FOXO and HLH-30/TFEB promote healthy aging in C. elegans, in part, by activating lipid metabolism genes that remodel lysosomes into tubular network...
www.nature.com
DAF-16/FOXO and HLH-30/TFEB comprise a cooperative regulatory axis controlling tubular lysosome induction in C. elegans - Nature Communications
Alyssa Johnson