Our research focuses on the synergy between #Synthetic #OrganicChemistry and #Technology. #ChemSky
Noel Research Group
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Self-driving labs are transforming chemistry; but high cost & complexity limit access to a few well-funded labs.
We wanted to change that.
Our new paper in #NatureSynthesis introduces RoboChem-Flex ๐งช๐ค
๐https://nature.com/articles/s44160-026-01053-0
#selfdrivinglab #flowchemistry #optimization
Self-driving labs are transforming chemistry; but high cost & complexity limit access to a few well-funded labs.
We wanted to change that.
Our new paper in #NatureSynthesis introduces RoboChem-Flex ๐งช๐ค
๐https://nature.com/articles/s44160-026-01053-0
#selfdrivinglab #flowchemistry #optimization
We combine ML + #DigitalTwins to autonomously design photoreactors with high light capture and uniform irradiation. A virtual photoreactor guides #BayesianOptimization, allowing numerous designs in silico and fabrication only of the best candidates.
๐ @chemrxiv.org : chemrxiv.org/engage/chemr...
We combine ML + #DigitalTwins to autonomously design photoreactors with high light capture and uniform irradiation. A virtual photoreactor guides #BayesianOptimization, allowing numerous designs in silico and fabrication only of the best candidates.
๐ @chemrxiv.org : chemrxiv.org/engage/chemr...
New @chemrxiv.bsky.social preprint!
RoboChem-Flex is a powerful, low-cost (<5k EUR), modular self-driving lab for chemical synthesis
We showcase 6 studies (photochemistry, biocatalysis, cross coupling, ee ...), all optimized with different configurations & ML
๐ chemrxiv.org/engage/chemr...
๐ We report a radical disconnection strategy that enables the direct, single-step conversion of ฮฑ-amino acids into differentiated vicinal diamines via photocatalytic decarboxylation.
Broad scope, functional-group tolerant, and scalable in flow.
๐ @chemrxiv.org: chemrxiv.org/engage/chemr...
๐ We report a radical disconnection strategy that enables the direct, single-step conversion of ฮฑ-amino acids into differentiated vicinal diamines via photocatalytic decarboxylation.
Broad scope, functional-group tolerant, and scalable in flow.
๐ @chemrxiv.org: chemrxiv.org/engage/chemr...
๐ฃ Thrilled to announce our incredible speaker lineup for the 2026 edition of #ETOC Online Symposium on April 29-30th.๐๏ธ Join us by registering today and to stay up-to-date! : tinyurl.com/ETOC2026-reg... (1/3)
Great talk by @dimanagornii.bsky.social from the group of Timothy Noรซl (@tnoel82.bsky.social) at #Lunteren2026. He talked about the late-stage modification of aryl compounds with NCF3 and SCF3 groups using flow chemistry.
chemrxiv.org/doi/full/10....
#ChemSky #FlowChemistry
First stop in USA East Coast lecture tour: Merck Rahway, great to discuss #FlowChemistry, #HTE, #SelfDrivingLabs and synthetic methodology with our friends in the pharma industry