Roulette is a basepair-resolution model for predicting germline de novo mutation rates across the human genome, helping uncover mechanisms that shape mutagenesis, including the impact of Polymerase III transcription.
Explore the tool: github.com/vseplyarskiy...
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A mutation rate model at the basepair resolution identifies the mutagenic effect of Polymerase III transcription - vseplyarskiy/Roulette