Official account for the Biological Psychiatry family of journals.
Publishing cutting-edge research in psychiatric neuroscience, cognitive neuroimaging, and global open science.
🎙️The Biological Psychiatry Podcast now live!
Biological Psychiatry
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Childhood maltreatment and genetic risk independently raise the likelihood of eating disorders, and their combined effect may further elevate risk for bulimia and binge-eating spectrum disorders.
Income losses during pregnancy can affect postpartum outcomes.
Dr. Pilyoung Kim explains the link between income losses and postpartum brain responses to infant cries.
Full episode: thebiologicalpsychiatrypodcast.riverside.com/e/prenatal-i...
Manic episodes influence brain connectivity in individuals with bipolar disorder
Dr. Leila Nabulsi explains how manic episodes might induce plasticity in the brain, driving reorganization of structural circuits.
Full episode: thebiologicalpsychiatrypodcast.riverside.com/e/hite-matte...
People with OCD show widespread hypoconnectivity compared to healthy controls, but the patterns vary considerably depending on specific symptoms, anxiety severity, and medication history.
Different executive function deficits are uniquely related to suicidal ideation and suicide attempts: deficits in task-switching and response inhibition are specifically related to suicidal ideation, whereas deficits in working memory and attentional control are specific to suicide attempts.
Youth at familial risk for bipolar disorder show brain-wide structural patterns similar to those in adults with the disorder, suggesting a potential brain-based marker that could help identify at-risk adolescents before symptoms fully emerge.
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People with schizophrenia show altered cerebellum-cerebrum dynamics during eye gaze perception that is linked to social dysfunction, suggesting the cerebellum might be an accessible target for brain stimulation therapies to improve social cognition.
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Young people with depression exhibit stronger negative connectivity between the default mode, salience, and dorsal attention networks, and the strength of the default mode-salience connectivity predicts treatment response.
Even when depression and anxiety symptoms improve in patients following brain stimulation therapy, anhedonia can persist, suggesting patients with severe anhedonia may need different treatment approaches.
Biological Psychiatry
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Biological Psychiatry
Although executive functioning deficits have been implicated in self-injurious thoughts and behaviors, the strength of their associations remain unclear. Few mechanisms reliably differentiating…
Bipolar Disorder (BD) is a severe mental illness, often emerging during adolescence, that is associated with significant psychosocial impairment. BD risk is elevated in offspring of affected parents,…
Individuals with schizophrenia have prominent impairments in social cognition that contribute to poor functional outcomes. Gaze processing – the social-cognitive ability to accurately perceive human…
Anhedonia is a core yet underrecognized symptom of major depressive disorder (MDD). Whether remission defined by Hamilton Depression (HAMD) and Hamilton Anxiety (HAMA) scales reflects improvement in…
Obsessive-compulsive disorder (OCD) has been associated with altered resting-state functional connectivity (FC), but findings are inconsistent and associations with clinical characteristics are…
Major depressive disorder (MDD) has been linked to altered resting-state functional connectivity between the default mode, salience, and task-positive networks. This study aimed to identify…
Genetic and environmental factors contribute eating disorder risk, yet their interplay is poorly understood. We examine whether childhood maltreatment and polygenic scores for anorexia nervosa…
