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Scientist, prof at Duke, mom, food, travel, ocean lover. Fascinated by how the brain develops and is modified in disease and evolution. RNA biology intersects neural development. Views my own not employer. https://sites.duke.edu/silverlab/
Debby Silver






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The choreography of development: RNA localization across time and space Chia-Fang Lee, @flydrbnl.bsky.social & @debbysilver.bsky.social highlight developmental roles for RNA localisation in cell polarity, fate and function across model organisms. journals.biologists.com/dev/article/...
16d
At Sfn? Join us at the Cajal Club Social! Sunday, Nov. 16th, 6:30PM–8:30PM. Salt & Whiskey bar@Horton Grand Hotel, www.hortongrand.com/dine-bar. We will learn about an exhibition on Cajal's Work and give out this year's awards to outstanding trainees and established scientists in our community!
heads up neuro bsky 😎 must-read seminal discoveries: ultimate translation of genetic information in the farthest reaches of the neuron ➡️ @erin-schuman.bsky.social & in cortex development ➡️ @debbysilver.bsky.social thanks again 🤝 @natrevneuro.nature.com Darran Yates for editorial collaboration
6mo
6mo
What a fantastic visit I had. Thanks so much @martinowk.bsky.social for hosting me and excited for future collaborations!
Delighted to share that our study is now out @cp-cellstemcell.bsky.social www.cell.com/cell-stem-ce... Congrats to Dr. @federicamosti.bsky.social for the culmination of a beautiful thesis!
22h
2mo
Development
Cajal Club
Debby Silver
Debby Silver
There's still time to apply to be a 2026 @dev-journal.bsky.social Pathway to Independence fellow For those about to apply for their first independent academic position, the programme offers - mentoring - leadership training - profile rising - networking journals.biologists.com/dev/pages/pi...
4mo
Pathway to Independence programme | Development | The Company of Biologists Development's Pathway to Independence programme Launched in 2022, Development’s Pathway Independence programm...
Pathway to Independence programme | Development | The Company of Biologists
journals.biologists.com
James Briscoe
“Intraspecific sequence variation and complete genomes refine the identification of rapidly evolved regions in humans” New work on HAQERs, by @rimangan.bsky.social Yanting Luo Craig Lowe @debbysilver.bsky.social @manoliskellis.bsky.social & colleagues 🧪🧬 www.biorxiv.org/content/10.1...
7mo
How human-specific DNA changes shape brain development is poorly understood. Mosti et al. discover a human enhancer, HAR1984, which drives ETV5 and TRA2B expression via human-enriched chromatin intera...
www.cell.com
Species-specific chromatin architecture and neurogenesis mediated by a human enhancer
Matthew L. Kraushar
The on-site, on-demand, neuronal gene machine — a Journal Club article by Matthew L. Kraushar @matthewkraushar.bsky.social #neuroscience #neuroskyence www.nature.com/articles/s41...
6mo
Cedric Boeckx
Sharing our newest study led by the incredibly talented @federicamosti.bsky.social investigating new molecular mechanisms of human brain development. We discover a human-specific enhancer HAR1984 that influences chromatin looping to promote cortical size and folding! www.biorxiv.org/cgi/content/...
Nature Reviews Neuroscience
10mo
Serving elevated comfort foods and classic handcrafted cocktails, Salt & Whiskey at the Horton Grand Hotel pays homage to grandeur of the Victorian era.
www.hortongrand.com
Salt & Whiskey - Horton Grand Hotel
Was stoked to host @debbysilver.bsky.social at @lieberinstitute.bsky.social today! Fantastic talk on her lab's work on molecular features that make the human 🧠 unique and how RNA localization shapes early neurodevelopment. Great conversations + exciting ideas for future collaborations - thx Debby!
1d
Debby Silver
Humans exhibit significant phenotypic differences from other great apes, yet pinpointing the underlying genetic changes has been limited by incomplete reference genomes and a reliance on single assemb...
www.biorxiv.org
Intraspecific sequence variation and complete genomes refine the identification of rapidly evolved regions in humans
Keri Martinowich