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Thrilled to see this in print! CarpeDeam is the first assembler built specifically for ancient metagenomics, as it specifically models aDNA damage. We also introduce "RYmers" (i.e., k-mers but robust to damage). Amazing work by Louis Kraft et al.! ⁠ genomebiology.biomedcentral.com/articles/10....
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De novo assembly of ancient metagenomic datasets is a challenging task. Ultra-short fragment size and characteristic postmortem damage patterns of sequenced ancient DNA molecules leave current tools i...
genomebiology.biomedcentral.com
CarpeDeam: a de novo metagenome assembler for heavily damaged ancient datasets - Genome Biology
Gabriel Renaud