Stem cell and developmental biologist, Professor @ University of Leuven, Belgium. #Pluripotency #Epigenetics
Vincent Pasque
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A stem-cell-based monkey embryo model that self-organizes into a comprehensive body plan could lead the way to more-sophisticated models of early human development
go.nature.com/48yxsG6
Continuous modeling of primate embryogenesis from totipotency to early organogenesis. Cell. www.cell.com/cell/abstrac...
I am very happy to share that I've started my new position @upcite.bsky.social and opened my lab @institutimagine.bsky.social 🎉
In the lab we will study how differences in X-linked gene dosage between the sexes affect fetal growth and survival and contribute to sex differences later in life 👩🔬🧪🧬🧫
Two decades of induced pluripotent stem cell research: From discovery to diverse applications
We are thrilled to share our new pre-print: “System-wide extraction of cis-regulatory rules from sequence-to-function models in human neural development”. S2F-deeplearning models can accurately encode enhancers, yet decoding these models into human-interpretable rules remains a major challenge.
Friends Davor Solter and Azim Surani receiving the wonderful Paul Ehrlich and Ludwig Darmstaedter Prize for Genomic Imprinting👏 👍 @Frankfurt Germany. With official talks from politicians using words like Education, Knowledge, Democracy 🙏 @maxplanck.de @gurdoninstitute.bsky.social
I look forward to presenting the work of the lab at the 2nd Meeting on Early Embryogenesis and Epigenetics in Berlin next week.
My talk will summarise ongoing work on early human development using naive pluripotent stem cells and embryo models.
www.molgen.mpg.de/embryo2026
Amazing and important work from Agenese Loda and colleagues! Happy to see this out. Congratulations to all co-authors.
Many thanks to Evans Bardot @ebardot.bsky.social and the editorial team for their thoughtful handling of this piece.
We have just published a tribute to John Gurdon, reflecting on his scientific legacy and the profound influence he had on generations of developmental biologists.
The piece is available open access in Nature Communications:
www.nature.com/articles/s41...
