//
sign in
Post
by @danabra.mov
PostEmbed
by @danabra.mov
Record
by @jimpick.com
Record
by @atsui.org
+ new component
Post
Beautiful new UK Wnt paper out now in @natgenet.nature.com by Peter Hohenstein, Andrew Wood and Derya Ozdemir @unileiden.bsky.social @edinburgh-uni.bsky.social and Koc University characterising the impact of numerous CTNNB1 mutational variants in human cancer. www.nature.com/articles/s41...
3mo
Saturation genome editing of a cancer mutation hotspot in CTNNB1, the gene encoding β-catenin, reveals a gradient of effects of missense mutations on Wnt signaling.
www.nature.com
Mutational scanning reveals oncogenic CTNNB1 mutations have diverse effects on signaling - Nature Genetics
WntUK