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Malnak, @bushmanlab.bsky.social et al. demonstrate how structural information can be used to overcome the limits of sequence-based methods and uncover fundamental principles of viral diversity and evolution. šŸ”— doi.org/10.1093/molbev/msag110 #evobio #molbio #virus
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Abstract. Pairwise sequence comparisons are at the center of molecular evolutionary analyses. However, viral pairwise comparisons are challenging because e
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Uncovering viral protein acquisition events and human-specific folds with pairwise comparisons of predicted protein structures
Molecular Biology and Evolution