Should biology put complexity first? www.sciencedirect.com/science/arti... - excellent essay by @philipcball.bsky.social. I would add epistasis to polygenicity and pleiotropy as a ubiquitous and fundamental phenomenon, not some optional complication that we can try to account for afterwards
The dictum “Everything should be made as simple as possible, but no simpler” poses a problem for biology. How simply can it be told without doing dama…