I am not sure how to do Bluesky yet, but I want to tell the world about our neighborhood NMF method. First of many collaborations with the Pelka Lab!!
Barbara Engelhardt
Super excited to tell you about our preprint on Neighborhood Nonnegative Matrix Factorization (NNMF) for spatially-aware dimension reduction in spatial transcriptomics, led by Ragnhild Laursen in collaboration with Karin Pelka @pelkalab.bsky.social and her lab!
www.biorxiv.org/content/10.1...
Tissues consist of multi-cellular neighborhoods in which different cell types express correlated gene programs due to shared signaling environments. Methods for identifying these spatial neighborhoods...
