EXO – Beyond the Cell is a quarterly, gold open-access journal published by Science Exploration Press.
www.sciexplor.com/exo contact: [email protected]
EXO - Beyond the Cell
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We have hundreds of secreted proteins.
But for many of them, their receptors remain unannotated: a major bottleneck in decoding intercellular communication.
A recent review highlights why ligand–receptor #deorphanization remains difficult: www.sciexplor.com/exo/articles...
#Spatialbiology #Secretome
Science: First Hormone Cell Atlas at single-cell resolution
Hormonal signaling is widely distributed across human cells. Secretin detected in immune cells; GLP-1 receptors in heart cells.
Led by Prof. Sarah Teichmann & HCA consortium.
Read: www.science.org/doi/abs/10.1...
#SingleCell #HumanCellAtlas
🎉New Mini Review on STAMP technology now published in EXO!
Title: Democratizing the spatial view: STAMP technology from an analytical perspective
By Drs. Poudel S, Dezem FS, Martelotto LG, Plummer JT, Green DR.
🔗Free to read: sciexplor.com/exo/articles...
#SpatialBiology #STAMP #Transcriptomics
How do cells talk to each other?
Researchers from Harvard Medical School lay out a roadmap to identify orphan signaling receptors using synthetic biology, AI, and spatial omics.
📰 www.eurekalert.org/news-release...
🔗 sciexplor.com/exo/articles...
#LigandReceptor #Deorphanization #SpatialOmics
💡Lymphatic endothelial cells aren’t just passive conduits.
They control T cell egress via autophagy & S1P, and can make or break immunotherapy.
Read the article by Diede Houbaert, @kathrynjacobss.bsky.social, and @agostinislab.bsky.social
🔗: sciexplor.com/exo/articles...
#tumorimmunology #autophagy
EXO - Beyond the Cell
💡 Is ferroptosis a spreading death wave rather than a cell-autonomous process?
A growing body of evidence suggests that #ferroptosis is not restricted to individual cells—but can propagate across tissues in wave-like patterns.
Read the article: www.sciexplor.com/exo/articles...
#CellDeath #lysosome
🧠 Could neuronal metabolism shape neurodegeneration?
A new review from Prof. David Rubinsztein’s team (Cambridge) links the mTORC1–autophagy axis to neurodegenerative diseases.
📄 eurekalert.org/news-release...
🔬 doi.org/10.70401/EXO...
#Neuroscience #Autophagy #Neurodegeneration
🎙️EXO Chats Podcast – Ep02 is LIVE!
Hosted by @brentstockwell.bsky.social , Dr. Kathryn Jacobs shares her journey in lymphatics study, the discovery blocking autophagy traps T cells & breaks immunotherapy, and her future vision of lymphatic modulation.
🔗Listen: youtube.com/watch?v=yvbo...
#Lymphatics
📢New Review Published in EXO!
Title: Computational workflows and data infrastructures for spatial omics analysis
By Drs. Jasmine Plummer, Mariah Alexander, Yutian Liu, Felipe Segato Dezem, and Hayden Chasteen
🔗Read: www.sciexplor.com/exo/articles...
#SpatialOmics
📢 New Review Published in EXO!
Title: Ferroptosis spreading through propagative signals
By Drs. Saloni K. Hombalkar, Jyotirekha Das, and Michael Overholtzer from @mskcancercenter.bsky.social
🔗 Open access: sciexplor.com/exo/articles...
#Ferroptosis #CellDeath #RedoxBiology
