PhD student studying phage-host interactions at ETH Zürich | Lab of Molecular Phage Biology
Dorentina Humolli
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Phage-encoded CasPRs transcriptionally silence diverse CRISPR-Cas systems https://www.biorxiv.org/content/10.64898/2026.02.23.707548v1
Happy to share our latest pre-print on the Druantia defense system.
We find that Type III Druantia uses a cooperative helicase-nuclease mechanism to sense and degrade replication-associated forked DNA structures.
www.biorxiv.org/content/10.6...
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🚨Preprint alert - this is a big one! We transfer the revolutionary power of TnSeq to bacteriophages.
Our HIDEN-SEQ links the "dark matter" genes of your favorite phage to any selectable phenotype, guiding the path from fun observations to molecular mechanisms.
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bioRxiv Microbiology
The "Research Day" at our department D-HEST is always caleidoscope of exciting science from food over health to medicine.
Phage biotechnology was well represented with Dorentina @humollidorentina.bsky.social and Enea @phagemuffin.bsky.social from our group and the lab of Martin Loessner. 🧫🧬🍻
🚨Preprint! Happy to share the research from my PhD “Genome delivery of a contractile tailed phage and its superinfection exclusion mechanism”. We use cryoEM to study the genome ejection of the phage T4, revealing how the tape measure protein regulates the process.
www.biorxiv.org/content/10.6...
Out Now! Conditional activation of Cas13 enforces lysogeny in a native type VI-A CRISPR host #MicroSky
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👻 Something strange in your liquid agar?
Who you gonna call? Thermophile hunters.
Our new @asm.org #MRA paper reports the complete genome sequence of Geobacillus stearothermophilus strain CS7089 isolated from a commercial agar preparation.
