Great work by Nicola De Maio and Nick Goldman - not just scaleable to "pandemic scale" trees but - if I have got this right - arguably more valid than traditional column based bootstrap in the context of very tight evolution.
Ewan Birney
During the COVID-19 pandemic, the millions of viral genomes coming in overwhelmed traditional methods for data analysis.
Find out how SPRTA, a new tool, provides a fast, scalable way to measure confidence of phylogenetic trees, helping scientists track outbreaks.
www.ebi.ac.uk/about/news/t...
A new method from EMBL-EBI and collaborators offers fast, easy-to-interpret confidence scores for phylogenetic trees for pandemic preparedness.