Wow! MARCH trial results show no significant benefit for hypertonic saline and carbocisteine in ventilated ICU patients, and significant harm associated with both. Very well done to all of the investigators!
www.nejm.org/doi/full/10....
#CCR26
Mucoactive agents are widely used in patients with acute respiratory failure despite
limited evidence of their effectiveness or safety. We conducted a multicenter, open-label,
randomized trial with...
