Excited to share our lab's latest preprint, led by graduate student Minhee Lee, with contributions from former undergrad Zijing Wang and grad student Andrew Johns!
We show that substrate specificity information coupled with AF3 models can be used to design selective tyrosine kinase inhibitors.
Neel Shah
Substrate-derived peptides for selective covalent inhibition of protein tyrosine kinases https://www.biorxiv.org/content/10.64898/2026.05.11.724146v1
