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Neuroscience.
Jan Gründemann









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Directional elements: the preprints are out! 1/n Congratulations to our amazing team: biorxiv.org/content/10.6... biorxiv.org/content/10.6... biorxiv.org/content/10.6... We screened for principles governing global brain dynamics by developing a set of new methods: 1) conformal immersion microscopy;
What can a neuron compute https://www.biorxiv.org/content/10.64898/2026.06.08.730984v1
Hippocampal CA2 modulates trace fear conditioning through circuit-specific control of CA1 https://www.biorxiv.org/content/10.64898/2026.06.05.730478v1
Mice produce interneurons in the septum as a response to aversive experiences and antidepressant treatment. www.science.org/doi/10.1126/...
New preprint from the lab. @markgergues.bsky.social and crew show that the PVT gates ventral hippocampal salience coding, shifting output between threat- and reward-weighted representations during associative learning and anxiety-related behavior. www.biorxiv.org/content/10.6...
🚨📢 New paper from the lab: Age-dependent vulnerability to spatial memory interference in APP/PS1 mice (a preclinical model of Alzheimer's disease) 🧵1/6 www.frontiersin.org/journals/agi...
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Spread the word: We’re hiring a Director of Operations to lead scientific support at the FMI. This senior role enables cutting-edge research by partnering with scientists, overseeing technology platforms, ensuring safety & compliance, and representing the FMI externally: www.fmi.ch/education-ca...
Two brain circuits. Same learning problem. Shared learning outcomes. Different dynamical implementations. Our work shows that learning is not a single canonical solution but can emerge through distinct population dynamics shaped by circuit architecture. Excited to share our latest preprint! 🧵1/12
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Excited to announce big steps for electrical imaging in the brain! In 4 preprints, we and collaborators present 2 new GFP-based voltage sensors: ASAP6c for high-throughput spike recordings, and ASAP7y for subthreshold 1P and 2P imaging bit.ly/4x3k3kX bit.ly/3RKZhq3 bit.ly/4o4fKl3 bit.ly/4uHXuk3 🧵