Assistant Professor at UW Genome Sciences developing/applying proteomic technologies | he/him/his | Views are my own.
Devin Schweppe
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Thrilled to announce that the Department of Microbiology at the University of Washington, School of Medicine is hiring at the Assistant Professor level (tenure-track)!
The Pacific Northwest is an awesome place to live and do science 🧪🦠. Join us!
apply.interfolio.com/185622
Applications due 8/1.
New work from @csneeze.bsky.social explored how common additives for thermal stability analyses affected protein-drug interaction hit calling.
We were surprised to see that buffer and method selection for lysates could recapitulate findings from in cell thermal stability assays!
☕ @riddhiman.bsky.social et al. use experimentally matched mass-spec and RNA-seq to quantify proteins, phosphosites & transcripts across 4 stages of human & mouse gastruloid development. @jshendure.bsky.social @leastarita.bsky.social @nobuhamazaki.bsky.social @dschweppe.bsky.social
bit.ly/4dAYyA1
If you are looking for a Tuesday evening #ASMS2026 workshop to attend, consider joining us for fun discussions about real time mass spectrometry.
new lab preprint - Protein function prediction is a well established problem but proteins exist in different post-translationally modified forms. Here, @julianvangerwen.bsky.social built a ML model to predict the biological process regulated by individual phosphosites www.biorxiv.org/content/10.6...
Patrick S. Mitchell
Garge et al. use experimentally matched mass spectrometry and RNA-sequencing to quantify proteins, phosphosites and transcripts across four key stages of human and mouse gastruloid development.
Excited to share our latest preprint from us at the Schweppe Lab detailing detergent impacts to thermal stability with consequences for thermal profiling: DDM behaves quite differently from NP-40 when used as a component of a melting buffer!
@dschweppe.bsky.social
www.biorxiv.org/content/10.6...
