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Asst. Prof. at MCB UConn 🔬🧬🏳️‍🌈 (He/él) #newPI Microbial Ecophysiology Lab https://microbial-ecophysiology-lab.mcb.uconn.edu/ Mexican & Indigenous, 1st gen #Methane #Microbes #Methanogen #Archaea #Microbiome #ArchaeaPower #OneHealth #Astrobiology #Proteins
Geo Santiago-Martínez









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We are only beginning to understand the breadth of enzyme diversity in the archaeal world. Here's an example of how an archaeon can deploy a phospholipase to kill certain bacteria... www.biorxiv.org/content/10.6...
To what extent #anaerobic #methanotrophic archaeal inputs may bias sea surf. T° reconstructed with #TeamArchaea hydroxylated isoprenoid tetraether lipids? @pierrickfenies.bsky.social et al. (2026) Org. Geochem.: www.sciencedirect.com/science/arti... #GDGTs #isoGDGTs 🧪 ⚒️ 🌊 Implications for #PaleoSky
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It’s clear that methanogen diversity and methane emissions from the GSL have been severely understudied and underestimated and that emissions will only worsen during lake drying. We hope to soon change that! Our research was funded by the NASA Exobiology (to Tim McDermott) and DOE BER (me) programs.
Hydroxylated isoprenoidal glycerol dialkyl glycerol tetraethers (OH-isoGDGTs) are used as sea surface temperature (SST) proxies through the RI-OH and …
www.sciencedirect.com
Impact of anaerobic methanotrophic archaeal input on hydroxylated isoprenoid GDGT-derived temperatures
Archaeal and eukaryotic MCM rings sequentially melt DNA for replication initiation @natcomms.nature.com #microbiology #archaea #eukaryotes #MicroSky doi.org/10.1038/s414...
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Cultivation and molecular profiling reveal ammonia-oxidizing archaea as skin commensals #microbiology #archaea #ammonia #MicroSky @isme-microbes.bsky.social doi.org/10.1093/isme...
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Archaea the hornets of the microbial world. Discuss. www.biorxiv.org/content/10.6... TLDR: Archaeon kills bacterium with secreted phospholipase. Pretty nifty way to kill bacteria if you are a microbe with a very different lipid make-up, I reckon. No need to worry about accidentally killing yourself.
To prepare for DNA replication, a short region of DNA base-pairs must be broken, termed melting, allowing a helicase to gain a foothold on an isolated DNA strand. Here, authors use single-particle cry...
doi.org
Archaeal and eukaryotic MCM rings sequentially melt DNA for replication initiation - Nature Communications
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Abstract. Ammonia-oxidizing archaea (AOA) have repeatedly been detected with molecular methods on human skin, yet their persistence, physiological traits,
doi.org
Evgenii Protasov
Cultivation and molecular profiling reveal ammonia-oxidizing archaea as skin commensals
Valerie Soo
Evgenii Protasov
Dr. Nina Davtian (she/her/hers)
A Bactericidal Phospholipase from Archaea
Archaea kill bacteria, at least on occasion. The molecular underpinnings of these lethal interactions are barely understood. Here, we describe cinquedea, an α/β hydrolase secreted by the halophilic ar...
www.biorxiv.org
Roland Hatzenpichler
‪ Archaea are the hornets of the microbial world. Discuss. www.biorxiv.org/content/10.6... TLDR: Archaeon kills bacterium with secreted phospholipase. Pretty nifty way to kill bacteria for a microbe with a very different lipid make-up, I reckon. No need to worry about accidentally killing yourself.
Archaea are the hornets of the microbial world. Discuss. www.biorxiv.org/content/10.6... TLDR: Archaeon kills bacterium with secreted phospholipase. Pretty nifty way to kill bacteria for a microbe with a very different lipid make-up, I reckon. No need to worry about accidentally killing yourself.
New paper out in Microbiology Spectrum: “Proteomic stress response by a novel methanogen enriched from the Great Salt Lake”, first author William Christian. We enriched a novel, euryarchaeotal, methyl-dismutating methanogen that grows at 16% salinity. 🦠 #microsky journals.asm.org/doi/full/10....
We named this archaeon in honor of Maurice Hilleman (1919-2005), a microbiologist and vaccinologist who graduated from Montana State University. Over the course of his career, he developed over 40 vaccines, including 8 that are recommended for children in the USA. His vaccines
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17h
Tobias Warnecke
17h
www.biorxiv.org
www.biorxiv.org
Methanogens are microbes that affect the climate through their production of the greenhouse gas, methane. Changes in climate and land-use patterns are drying up saline lakes, damaging their unique eco...
journals.asm.org
Proteomic stress response by a novel methanogen enriched from the Great Salt Lake | Microbiology Spectrum
Tobias Warnecke
Tobias Warnecke
A Bactericidal Phospholipase from Archaea
Archaea kill bacteria, at least on occasion. The molecular underpinnings of these lethal interactions are barely understood. Here, we describe cinquedea, an α/β hydrolase secreted by the halophilic ar...
www.biorxiv.org
Roland Hatzenpichler
Roland Hatzenpichler
Archaea are the hornets of the microbial world. Discuss. www.biorxiv.org/content/10.6... TLDR: Archaeon kills bacterium with secreted phospholipase. Pretty nifty way to kill bacteria for a microbe with a very different lipid make-up, I reckon. No need to worry about accidentally killing yourself.
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www.biorxiv.org
Tobias Warnecke