Prof TT Uni Bonn & University Hospital Bonn | RNA & ribosome & biochemistry & innate immunology | Postdoc Barna Lab Stanford | PhD Stoecklin Lab DKFZ ZMBH Uni Heidelberg | triplet | https://www.leppeklab.org
Kathrin Leppek
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3/5 We test IRES features in circRNAs:
• synthetic circRNA translation in cells and in cell-free extracts
• IRES identity (viral vs cellular) and translation activity in circRNAs
• immunogenicity of circRNAs dependent on purity and IRES identity
• engineering of IRES-mediated circRNA translation
Not what you want to see on an evening after a holiday, or ever. #VEwater