Neuroscientist at University College London (www.ucl.ac.uk/cortexlab). Opinions my own.
Matteo Carandini
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🪼 Your tax dollars paid a scientist to squeeze jellyfish through cheesecloth. Osamu Shimomura processed tens of thousands on an NSF grant to understand why they glow. He found a protein that glowed green under UV light. Called it "green protein." Nobody cared. For decades.
Neuropixels + Optogenetics = Neuropixels Opto
Combining high-resolution electrophysiology and optogenetics. 960 sites, 28 emitters, 2 colors.
Today in @natmethods.nature.com
doi.org/10.1038/s415...
Thanks to @wellcometrust.bsky.social, @alleninstitute.org, @hhmijanelia.bsky.social & team.
Marjane Satrapi, author of 'Persepolis,' dies at 56
Video
The French-Iranian 'died of sadness a little over a year after the death of Mattias Ripa, her husband and the love of her life,' people close to her said.
Scientists are raising the alarm about a White House proposal that could fundamentally recast federally funded science. The proposed rules would put political appointees in control of all federal grants and de-emphasize peer review, among other measures.
go.nature.com/4ucZgsk
TK (Takashi DY) Kozai
Matteo Carandini
Mice use the same thalamocortical pathway to decode orientation selectivity established by Hubel and Wiesel in cats, showing that this visual feature “is preserved through evolution,” says Jose-Manuel Alonso. #neuroskyence
By @claudia-lopez.bsky.social
www.thetransmitter.org/vision/unbel...
The Trump administration’s proposal aims to improve transparency in federal funding, but critics fear the proposed rules would politicize research
Interesting article on something I think is very relevant to open science: several teams analyzed the same ephys dataset and got quite different answers.
Not because the analyses were bad, but because this kind of work involves many analysis choices, and those choices can change the result.
Nature
A breakthrough technology, co-developed by UCL scientists, that records and manipulates neuron activity deep within the brain could transform our understanding of neural circuits and neurological conditions.
@carandinilab.net @ucleye.bsky.social @alleninstitute.org
www.ucl.ac.uk/news/2026/ju...
Orientation tuning—the ability to distinguish a horizontal line from a vertical one or something in between—originates in the visual cortex.
I support @sfn.org and I don't think they'd ever do anything like this. But news like this make world scientists want to avoid the US. For instance, this year our lab is skipping the US neuroscience meeting, in favor of the @fens.org meeting in Barcelona. (See you there!)
Differences stemmed from the way researchers defined concepts, to the algorithms they used to analyze the data, to the parameters they employed when implementing the algorithms, note @mattiachini.bsky.social and Gaelle Chapuis. #neuroskyence
www.thetransmitter.org/reproducibil...
A new technology that simultaneously records and manipulates neuron activity deep within the brain could transform our understanding of neural circuits and neurological conditions. Co-authored by @carandinilab.net at @ucleye.bsky.social. In @natmethods.nature.com. www.ucl.ac.uk/brain-scienc...
UCL Faculty of Brain Sciences
Yup. Sitting on a 3% scored R01 since Jan and I still don’t know if it’s getting funded. This is just not sustainable. How is the NIH going to spend its mandated budget?!
Matteo Carandini
Disagreement in neuroscience runs deeper than most researchers suspect—even in electrophysiology, a field that prides itself on hard data.
NEW: They Got the Best NIH Scores of Their Careers. A Year Later, They Still Don’t Have Funding.
As the NIH bankrolls new research at a significantly slower-than-usual pace, I talked to scientists left in the lurch about the toll on their research and careers: www.chronicle.com/article/they...
The NIH’s spending on new medical research is significantly slower than in previous years, leaving confused scientists in the lurch.
Scientists ejected from diabetes conference for distributing journal reprints of editorial critical of the Trump administrations's ongoing attacks on science. Those ousted included ADA journal editor-in-chief Steven Kahn and former ADA president Desmond Schatz arstechnica.com/science/2026...
A breakthrough technology, co-developed by UCL scientists, that simultaneously records and manipulates neuron activity deep within the brain could transform our understanding of neural circuits and ne...
www.ucl.ac.uk
Those ousted included ADA journal editor-in-chief Steven Kahn and former ADA president Desmond Schatz...