Interdisciplinary research centre at the University of Warwick (UK) with the mission to understand active self-organisation of living systems with a focus on molecular machines, cellular interfaces and tissue mechanobiology
Centre for Mechanochemical Cell Biology
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Kristen talks about kinesins that damage the microtubule track they walk on. Adding EB1 exacerbates microtubule destruction while CLASP protects. She also describes her work to understand how tracks are modified enzymatically and how this correlates to lattice expansion and tubulin tail availability
We had a blast. Thanks to everyone who came and made this such a memorable event.
What happens when science is free to ask any question?
It leads to discoveries we didn’t plan for – but now depend on.
This #EuropeDay, we support #ProtectWhatMatters, celebrating the freedom that makes frontier research possible.
Read the stories 👉 buff.ly/SRCDWoW
and have a happy Europe Day! 🇪🇺
A mystery at @mechanochemistry.org !
There’s a carrot that is neatly placed in the corridor. None is admitting to owning it. How did it get here? Where will it go next? 🥕
Centre for Mechanochemical Cell Biology
10 years Bowman lab @bowchro.bsky.social anniversary today, so we are treated to a complete history with all side bets talk. Congratulations 🎉
Last but not least, Kristen Verhey's @kjverhey1.bsky.social closing keynote. She starts off with her top 5 of Rob's papers over the years
Mark Dodding @markdodding.bsky.social talks about cargo-dependent activation of kinesin-1 through the light chain. Phosphorylation by NEK10 kinase suppresses membrane association of KLC2 specifically and controls lysosome transport by cooperation with cargo adapters.
Varun Ramaswamy is describing how he tackled the difficult problem of determining the structure of full length of HSET
Our own Masanori Mishima is up next discussing weak electrostatic interactions of motors and tracks that can be regulated by post translational modifications with examples from phosphorylation of KIF23/MKLP1 and arginylation and myosin II.
Erik Schäffer @schaefferlab.bsky.social uses silicon nanospheres to measure the forces of ultra-weak plant kinesins with sub femtoNewton resolution.