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by @jimpick.com
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Our new preprint is out! Led by @stefanosala89.bsky.social sky.social we investigate the difference between molecular tension sensing and global tension on the focal adhesion. Follow along for a thread of our findings: www.biorxiv.org/content/10.1...
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www.biorxiv.org
Mechanotransduction is fundamental to cell signaling and depends on force-sensitive adhesion proteins. How these proteins differentiate and integrate their responses to tension remains an open questio...
LIM Domain Proteins link molecular and global tension by recognizing strained actin in adhesions
Patrick Oakes