Researcher @Jiri Lukas lab, Novo Nordisk Center for Protein Research, Genome Instability, CRISPR-Cas9, heritable consequences of DNA repair, single cell high content screening, greenify research ๐ฑ
Susi Bantele
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Our latest collaboration with the talented Susi @sbantele.bsky.social and Jiri Lukas is out now @science.org ๐คฉ. We reveal the hidden price for DNA repair, with potential implications for genome function, gene therapy and ageing๐
๐๐ฎ๐ป ๐ฐ๐ฒ๐น๐น๐ ๐ฒ๐๐ฒ๐ฟ ๐๐ฟ๐๐น๐ ๐ฟ๐ฒ๐ฐ๐ผ๐๐ฒ๐ฟ ๐ณ๐ฟ๐ผ๐บ ๐๐ก๐ ๐ฑ๐ฎ๐บ๐ฎ๐ด๐ฒ?Excited to share our new study โRepair of DNA double-strand breaks leaves heritable impairment to genome functionโ, revealing DNA repairโs hidden cost, out now @science.org tinyurl.com/5n6zw3ye. Led by @sbantele.bsky.social and Jiri Lukas.๐งต๐1/n
The Groth lab
Upon DNA breakage, a genomic locus undergoes alterations in three-dimensional chromatin architecture to facilitate signaling and repair. Although cells possess mechanisms to repair damaged DNA, it is ...
