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Happy to share our new study that was just published in Neuron! www.cell.com/neuron/fullt...
Mar 28, 2025
TDP-43 pathology characterizes neurodegenerative diseases. Scialò et al. use in vitro-generated and patient-derived TDP-43 aggregates as seeds to show that seed-induced TDP-43 cytoplasmic aggregation ...
www.cell.com
Seeded aggregation of TDP-43 induces its loss of function and reveals early pathological signatures
Polymenidou Lab