Vanderbilt PhD Candidate - Cell and Developmental Biology | Tyska Lab | Microscopy, cytoskeleton, and mechanics of microscopic life 🔍
Zachary Lehmann
Good sampling on this confocal volume of small intestinal tissue showing the apical shag carpet (blue is F-actin, magenta is ZO1)🔬🤩
@vucellimaging.bsky.social
#microscopy #cytoskeleton #epithelial #cellbiology #biology
Happy #FluorescenceFriday! These are polarized epithelial cells with microvilli on their apical surface! Captured using the #Nikon NSPARC, and color-coded by depth #actin #microscopy @tyskalabactual.bsky.social
Have you always wondered how microvilli form? Where DOES that actin come from to form the core bundle? Come to the #BuildingTheCell (Part 1) subgroup tomorrow morning at 8:45 to find out! Room 29C. #CellBio2025
@tyskalabactual.bsky.social
Video
New Burnette Lab Preprint!
A non-muscle α-actinin is an intrinsic component of the cardiac Z-disc and regulates sarcomere turnover, contractility, and heart remodeling
www.biorxiv.org/content/10.1...
Colorful projections of filopodial tips imaged with TIRF microscopy for #FluorescenceFriday @tyskalabactual.bsky.social
It's #FluorescenceFriday fresh off the press is this depth coded image of #Microtubules. @tyskalabactual.bsky.social
Also, also on Monday at #cellbio2024 I get to present Olivia’s (@operkins.bsky.social) unexpected discoveries on the link between clathrin-mediated endocytosis and the growth of epithelial microvilli 🤯
P1831. B137.
@vucellimaging.bsky.social
Thought Spef1 one was some ciliary protein? Check out Dr. Rocio‘s (@rtpastrana.bsky.social) poster on how Spef1 shapes epithelial monolayers, no cilia needed 🤩. Tuesday at #cellbio2024, P2439, B46. @vucellimaging.bsky.social
Posters on tuft cells are about as rare as tuft cells, but at #cellbio2024 on Monday, @jen-silverman.bsky.social presents “P1718. Organization of a cytoskeletal superstructure in the apical domain of intestinal tuft cells. B23” Yes! those are gigantic actin bundles 🤯
@vucellimaging.bsky.social
Also Monday at #cellbio2024! Julissa (@yuyi106.bsky.social) will present her studies on the role of an I-BAR protein (IRTKS) in the pathogenic mechanism of Enterohemorrhagic E. coli 🦠🧫🔬 P2352. B677. @vucellimaging.bsky.social
Video
Matt Tyska
Cardiac sarcomeres generate the fundamental forces behind each heartbeat and are thought to contain only muscle-specific cytoskeletal proteins. We show that a widely expressed actin cross-linking prot...
