The Betz Lab is interested in the mechanics of cellular systems especially concerning cancer progression, collective cell migration and cell fate decision.
You are a biologist and want to get an idea why looking at intracellular active mechanics is important for cellular function? Check out our recent review preprint: arxiv.org/abs/2501.14538. We try to give an intuitive access, but also provide details in extensive toolboxes.
Getting tissue stress from images is tough, and elastic tension sensors are a way to solve this. Still, the analysis is complex. Try our GUI gitlab.gwdg.de/betzlab_publ... implementing analytical solutions to obtain surface stresses AND shape parameters of beads and nuclei.
Check out the paper here: www.biorxiv.org/content/10.1...
Betzlab
The measurement of stresses and forces at the tissue level has proven to be an indispensable tool for the understanding of complex biological phenomena such as cancer invasion, embryo development or w...
